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KMID : 0363220080460060835
Korean Journal of Dermatology
2008 Volume.46 No. 6 p.835 ~ p.838
A Case of Actinic Cheilitis Treated by Topical Photodynamic Therapywith Methyl Aminolevulinate
Huh Chang-Hun

Lee Hye-In
Rho Yong-Kwan
Kim Beom-Joon
Kim Myeung-Nam
Song Kye-Yong
Lee Ju-Hee
Abstract
Actinic cheilitis is a pathologic condition affecting mainly the lower lip caused by long term exposure of the lips to UV radiation in sunlight. Analogous to actinic keratosis of the skin, actinic cheilitis is considered as a precancerous lesion and may develop into squamous cell carcinoma. Photodynamic therapy (PDT) is a treatment modality involving the use of a photosensitizing agent, oxygen, and light of a specific wavelength to produce controlled cell death. Photodynamic therapy (PDT) using the new highly selective photosensitizer methyl aminolevulinate (MAL) (Metvix¨Þ, Galderma, U.K.) is a promising new treatment modality for premalignant and malignant skin lesions. We report a case of actinic cheilitis treated with PDT using MAL, with satisfactory outcome in both clinical and pathological aspects. (Korean J Dermatol 2008;4 (6):835¡­838)
KEYWORD
Actinic cheilitis, Methyl aminolevulinate, Photodynamic therapy
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